Module: General Genetics I (2401-210)

Persons:

• Prof. Dr. Anette Preiss (verantwortlich)

Degree Program:

• Biologie Lehramt an Gymnasien (Master, since 01.10.2017)
  3. Semester, elective
• Biologie Lehramt an Gymnasien (Master, since 01.10.2017)
  1. Semester, elective
• Biologie Lehramt an Gymnasien | Erweiterungsmaster (Master, since 01.10.2017)
  3. Semester, elective
• Biology (Bachelor, since 01.04.2011)
  5. Semester, semi-elective
• Nutritional Science (Bachelor, since 01.04.2011)
  5. Semester, elective

Relation to other Modules:

This module forms together with the modules "General Genetics II" and "General Virology" the elective profile Genetics for the study programme "Biology"

Prerequisites for Attendance:

Knowledge equivalent to the modules "Genetics" and "AMB II"

Sprache:

German

ECTS:

6 credits

Frequency:

every winter semester

Length of the Module:

1 semester

Compulsory assignment:

Regular and active participation, seminar lecture and colloquium covering the topics of the seminar

Module examination:

Written exam covering the topics of the lecture

Length of the examination:

120 minutes

Workload:

58 h presence + 122 h personal contribution = 180 h workload

Professional competences:

Lecture:
- Molecular mechanisms of replication
- Molecular mechanisms of recombination; mosaic analysis
- Transcriptional control; structure of regulatory elements
- Molecular mechanisms of translation
- Gene evolution
- Genetic screens; mobile elements
- Inducible systems; technology of LOF/GOF genetics
- Genetics of the immune system
- Fundamental signalling pathways and cell cell communication
- Molecular regulation of the cell cycle and apoptosis
- Molecular genetics of tumorigenesis

Seminar:
Each student presents a genetics paper, which is discussed afterwords. Topics include:
- New ways of cloning genes
- Overexpression Screens in Drosophila
- Modern transgenesis in Drosophila
- Generating mutants with Crispr/Cas9 in Drosophila
- Structure-function analysis of Notch signalling molecules
- Analysis of the Notch repressor complex
- Cross-talk between Notch- and other signalling pathways

Key competences:

- electronic search of original scientific literature
- extraction of relevant contents
- preparation and presentation of scientific literature in a comprehesible manner for a general audience
- scientific discussion

Comments:

Maximum number of participants: 23

eLearning:

Course in ILIAS

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