Course: Ion Transporters (1301-452)

Persons:

• Prof. Dr. Julia Fritz-Steuber (verantwortlich)

Type of Course:

lecture

In-Class Hours Per Week:

1

Contents:

The molecular basis for the biological function of ion transporters will be discussed. A focus is on systems for active and passive transport of Na+, K+ and Ca2+.
Topics:
- The electrochemical membrane potential
- Physiological relevance of Na+, K+, Ca2+
- Primary producers of the electrochemical potential (cation pumps)
- How channels work/how to study channels
- Voltage- versus ligand-gated channels
- Structure-function analysis of ion transporters
- Comparing transport rates and ion selectivities of different systems

Literature:

Ashcroft, F. M.: Ion Channels and Disease. Academic Press

Location:

Hohenheim

Remarks:

The lecture is suited as additional course for students of other scientific Master's programmes.

Module:

• 1301-450 Metal Coordination Chemistry in Biomolecules (compulsory)

eLearning:

Course in ILIAS