Course: Bioinorganic Chemistry (1301-451)

Persons:

• Prof. Dr. Henry Strasdeit (verantwortlich)

Type of Course:

lecture

In-Class Hours Per Week:

2

Contents:

Molecular foundations of the biological functions of metals; overview of biologically important metal ions and ligands; some principles of metal coordination chemistry; the basis of metal ion homeostasis; toxic metal ions; biological electron transfer: cytochromes, iron-sulfur proteins, blue copper proteins; „synthetic analogues“ concept; biological Lewis acid catalysis: carboxypeptidase, carboanhydrase, aconitase; transport of molecular oxygen: hemoglobin, hemerythrin, hemocyanine; structural functions of metal ions: calmodulin, zinc finger proteins; transport and storage of metal ions; physical methods for the characterization of metal ion-containing biomolecules (e. g. protein crystallography).

Literature:

Kaim, W., Schwederski, B., and Klein, A.: Bioinorganic Chemistry - Inorganic Elements in the Chemistry of Life. Wiley, Chichester, 2013

Location:

Hohenheim

Remarks:

The lecture is suited as additional course for students of scientific Bachelor's programmes (from the 4th semester on) and other scientific Master's programmes.

Module:

• 1301-450 Metal Coordination Chemistry in Biomolecules (compulsory)

eLearning:

Course in ILIAS